MOTS-c

Mitochondrial Signaling • Metabolic Adaptation • Longevity Research

MOTS-c is a mitochondrial-derived peptide (MDP) studied for its role in cellular energy regulation, metabolic flexibility, and stress adaptation. Unlike traditional peptides encoded in nuclear DNA, MOTS-c originates from mitochondrial DNA, making it a unique compound in mitochondrial communication, metabolic resilience, and longevity research.

MOTS-c is widely explored in research models focused on exercise adaptation, insulin sensitivity signaling, and age-related metabolic decline.

Key Research Highlights

⚡ Mitochondrial Energy & Metabolic Signaling

MOTS-c is studied for its ability to influence cellular energy balance by regulating metabolic pathways involved in glucose utilization and fatty-acid oxidation.

🔥 Exercise & Stress-Adaptation Research

Research models associate MOTS-c with exercise-mimetic signaling, supporting cellular responses typically activated during physical stress and endurance activity.

⚖️ Insulin Sensitivity & Metabolic Flexibility

MOTS-c is explored for its role in improving metabolic adaptability, particularly in models examining insulin signaling and glucose handling.

🧬 Longevity & Cellular Aging Research

As a mitochondrial-encoded peptide, MOTS-c is closely linked to aging research focused on mitochondrial communication, metabolic resilience, and cellular longevity pathways.

🛡️ Cellular Stress Resistance

MOTS-c is studied for its potential role in protecting cells against metabolic and oxidative stress, supporting overall cellular stability in adverse conditions.

How It Works

MOTS-c acts as a signaling peptide that communicates mitochondrial status to the nucleus, helping regulate metabolic gene expression. By influencing pathways related to energy sensing and stress response, researchers study MOTS-c as a key mediator of mitochondrial-nuclear cross-talk and metabolic adaptation.

Common Research Applications

Mitochondrial signaling and communication studies
Metabolic flexibility and insulin-response research
Exercise-adaptation and endurance signaling models
Longevity and metabolic aging research
Cellular stress-response and resilience studies

Suggested Use

For research purposes only. Usage protocols vary depending on experimental design and research objectives.

Important Disclaimer

This product is intended for research use only. Not intended to diagnose, treat, cure, or prevent any disease. Not for human consumption.